In addition to overseeing strategic communications planning for Closing the Treatment Gap, Debra Rubino is responsible for the creation and implementation of an integrated communications platform for OSI-Baltimore, including publications, public relations, electronic media, and events, especially to support the Campaign for Baltimore.

From 1998 to January 2006, Rubino served as vice president for communications at Goucher College, and was responsible for creating a new, comprehensive identity for the college, which had been a former women's college. From 1988-1996, she served first as director of institutional communications at the Maryland Institute College of Art, and then from 1996-1998, as associate vice president. At MICA, she was one of six individuals from different colleges and universities who worked to launch the Baltimore Collegetown Network, a consortium of 15 institutions from the region. After the Baltimore Collegetown Network established itself as a 501(c)(3), Rubino served as the Governing Board's president for five years.

An active professional artist, Rubino also works as a photographer and printmaker. She serves on the board of the Greater Baltimore Cultural Alliance and Art on Purpose. She holds a BA degree from Franklin and Marshall College and an MFA from the Maryland Institute College of Art.